Paradoxical effects of temperature in multiple sclerosis. |
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| Authors: | W P Honan J R Heron D H Foster R S Snelgar |
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| Affiliation: | Department of Neurology, North Staffordshire Royal Infirmary, Stoke-on-Trent, UK. |
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| Abstract: | Six cases of multiple sclerosis are reported in which cold produced a temporary exacerbation of symptoms and signs of the disease. Also, in one case investigated in detail by psychophysical methods, heating produced a paradoxical deterioration in vision and simultaneous improvement in sensory and motor function. The effect of temperature in multiple sclerosis is discussed and a physiological explanation for the paradoxical response to heating is suggested. |
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