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| UPLC测定银黄颗粒中绿原酸、咖啡酸、黄芩苷、汉黄芩苷、黄芩素和汉黄芩素6种成分 | |
| 引用本文： | 张建伟,赵倩,何希荣,冯伟红. UPLC测定银黄颗粒中绿原酸、咖啡酸、黄芩苷、汉黄芩苷、黄芩素和汉黄芩素6种成分[J]. 中国实验方剂学杂志, 2014, 20(18): 50-53 |
| 作者姓名： | 张建伟 赵倩 何希荣 冯伟红 |
| 作者单位： | 1. 河南中医学院第二附属医院河南省中医院肾内科,郑州,450002 2. 中国中医科学院中药研究所,北京 100700;中药质量控制技术国家工程实验室,北京 100700 3. 中国中医科学院中药研究所,北京,100700 |
| 基金项目： | 国家“重大新药创制”科技重大专项（2009ZX09301-005，2009ZX09308-003） |
| 摘 要： | 目的:建立采用UPLC同时测定银黄颗粒中绿原酸、咖啡酸、黄芩苷、汉黄芩苷、黄芩素和汉黄芩素6种成分含量的方法。方法:采用ACQUITY UPLC BEH C18色谱柱(2.1 mm×50 mm,1.7μm),流动相乙腈-0.2%磷酸水梯度洗脱,在326nm波长处进行检测。结果:绿原酸、咖啡酸、黄芩苷、汉黄芩苷、黄芩素和汉黄芩素的线性关系良好,加样回收率分别为96.34%(RSD 0.90%),101.4%(RSD 1.53%),95.64%(RSD 1.34%),98.01%(RSD1.72%),98.61%(RSD 1.96%),102.7%(RSD 1.42%)。结论:该方法简便、快速,分离效果好,可为全面控制银黄颗粒的质量提供参考。 |
| 关 键 词： | 超高液相色谱 银黄颗粒 绿原酸 咖啡酸 黄芩苷 汉黄芩苷 黄芩素 汉黄芩素 |
| 收稿时间： | 2014-04-01 |
Simultaneous Determination of Six Flavones in Yinhuang Granule by UPLC |
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| ZHANG Jian-wei,ZHAO Qian,HE Xi-rong and FENG Wei-hong. Simultaneous Determination of Six Flavones in Yinhuang Granule by UPLC[J]. China Journal of Experimental Traditional Medical Formulae, 2014, 20(18): 50-53 | |
| Authors: | ZHANG Jian-wei ZHAO Qian HE Xi-rong FENG Wei-hong |
| Affiliation: | The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine(TCM), Department of Naphrology of Henan TCM Hospital, Zhengzhou 450002, China;Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China;National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines, Beijing 100700, China;Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China;Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China;National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines, Beijing 100700, China |
| Abstract: | |
| Keywords: | UPLC Yinhuang granule chlorogenic acid caffeic acid baicalin wogonoside baicalein wogonin |
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