复方中药对主动吸烟动物祛痰作用的研究

目的　观察复方中药对动物主动吸烟的祛痰作用。方法　采用小鼠酚红祛痰法、大鼠毛细管集痰法及蟾蜍口腔粘膜纤毛运动测定法,研究复方中药雾化吸入及药物香烟对动物主动吸烟模型的祛痰作用。结果　复方中药高剂量雾化吸入明显增加主动吸烟小鼠痰量(P <0 .0 5 ) ;药物烟高剂量组能明显增加小鼠与大鼠的痰量(P <0 .0 5 ) ,加速蟾蜍口腔粘膜纤毛运动(P <0 .0 5 )。结论　复方中药对动物主动吸烟有一定的祛痰作用。

Observation on expectorant action of traditional Chinese herb compound in the active smoking animal model

Objective To observe the expectorant action of traditional Chinese herb compound(TCHC)on the active smoking animal model. Methods Phenolsulfonphthalein excretion from respiratory tract for mice, capillaries gathering phlegm for rats and mouth ciliary motion for toads were employed to investigate the expectorant action of TCHC. Results The findings showed that expectorant action in inhalation of aerosolized TCHC produced better results than that in cigarette smoking group in mice(P<0.05), and smoking cigarette contained TCHC were all better than that in cigarette smoking group in mice and rats. Mouth ciliary motion for toads were found to be faster than that in cigarette smoking group contained TCHC(P<0.05). Conclusion The data obtained illustrate that TCHC has certain expectorant action in the active smoking animals.