| 冬虫夏草菌丝对慢性乙肝T细胞亚群和肝纤维化指标的影响 |
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| 引用本文： | 龚环宇,万克青,唐世刚. 冬虫夏草菌丝对慢性乙肝T细胞亚群和肝纤维化指标的影响[J]. 中南大学学报(医学版), 2000, 25(3): 248 |
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| 作者姓名： | 龚环宇 万克青 唐世刚 |
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| 摘 要： | 为了探索治疗慢性乙型肝炎有效的药物 ,本文应用冬虫夏草菌丝治疗慢性乙肝患者 2 5例 ,分别于治疗前后观察其外周血T淋巴细胞亚群CD4,CD8;血清肝纤维化指标透明质酸 (HA)和前Ⅲ型胶原 (PCⅢ )。治疗 3月后 ,CD4,CD4 CD8,HA ,PCⅢ与治疗前相比差异有显著性 (P <0 .0 5 ) ,且与对照组相比差异亦具有显著性 (P <0 .0 5 )。而对照组治疗前后的变化无显著性。提示冬虫夏草菌丝对调节慢性乙肝患者细胞免疫水平和抗肝纤维化有一定作用
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| 关 键 词： | 乙型肝炎 冬虫夏草菌丝 T淋巴细胞亚群 肝纤维化 治疗应用 |
Effects of cordyceps sinensis on T lymphocyte subsets and hepatofibrosis in patients with chronic hepatitis B |
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| GONG Huanyu,WANG Keqing,TANG Shigang. Effects of cordyceps sinensis on T lymphocyte subsets and hepatofibrosis in patients with chronic hepatitis B[J]. Journal of Central South University. Medical sciences, 2000, 25(3): 248 |
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| Authors: | GONG Huanyu WANG Keqing TANG Shigang |
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| Affiliation: | Department of Infectious Disease, The Third Affiliated Hospital, Hunan Medical University (Changsha 410013) |
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| Abstract: | In order to find an effective drug to cure patients with chronic hepatitis B, cordyceps sinensis had been used to treat 25 patients with chronic hepatitis B. The comprehensive indexs, including T lymphocyte subsets(CD 4, CD 8), hyaluronic acid(HC) and precollagen type Ⅲ(PC Ⅲ), were observed before and after treatment. After 3 months of treatment, CD 4 and CD 4/CD 8 ratio increased significantly(P<0.05), while HA and PC Ⅲ decreased significantly(P<0.05) compared with the control. The results suggest that the benificial effects might be obtained by using cordyceps sinensis to adjust the T lymphocyte subsets level and to treat hepatic fibrosis on patients with chronic hepatitis B |
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| Keywords: | hepatitis B cordyceps sinensis T lymphocyte subsets hepatofibrosis therapy use |
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