| 脂肪因子和代谢综合征 |
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| 引用本文： | Zhou LB,Chen MD. 脂肪因子和代谢综合征[J]. 中国医学科学院学报, 2006, 28(6): 840-844 |
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| 作者姓名： | Zhou LB Chen MD |
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| 作者单位： | 上海交通大学医学院,附属瑞金医院内分泌代谢科,上海市内分泌代谢病研究所,上海,200025 |
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| 摘 要： | 脂肪组织被认为不仅是能量储存器官,而且是功能活跃的内分泌器官。脂肪因子在代谢综合征的发生、发展过程中起重要作用,尤其是肥胖时内脏脂肪组织分泌的促炎症脂肪因子可直接导致胰岛素抵抗和血管损伤,充分理解脂肪组织的内分泌功能将有助于对代谢综合征作出更合理的治疗。
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| 关 键 词： | 脂肪因子 代谢综合征 脂肪细胞 炎症 动脉粥样硬化 |
| 文章编号： | 1000-503X（2006）06-0840-05 |
| 收稿时间： | 2006-06-05 |
| 修稿时间： | 2006-06-05 |
Adipokine and metabolic syndrome |
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| Zhou Li-bin,Chen Ming-dao. Adipokine and metabolic syndrome[J]. Acta Academiae Medicinae Sinicae, 2006, 28(6): 840-844 |
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| Authors: | Zhou Li-bin Chen Ming-dao |
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| Affiliation: | Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrinology, Rui-Jin Hospital; Shanghai Jiaotong University School of Medicine, Shanghai 200025, China |
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| Abstract: | Adipose tissue is not simply a depot of energy, but is an active endocrine organ. The adipo- kines play an important role in the pathogenesis of metabolic syndrome. The proinflammatory adipokines secreted from expanded visceral adipose tissue directly induce insulin resistance and vascular injuries. A better understanding of the endocrine function of adipose tissue may lead to more rational therapy for metabolic syndrome. |
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| Keywords: | adipokine metabolic syndrome adipocyte inflammationl atherosclerosis |
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