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Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-kappaB and AP-1 as prime targets
Authors:Kundu Joydeb Kumar  Shin Young Kee  Surh Young-Joon
Institution:National Research Laboratory of Molecular Carcinogenesis and Chemoprevention, College of Pharmacy, Seoul National University, Shinlim-9-dong, Kwanak-gu, Seoul 151-742, South Korea.
Abstract:
Keywords:AP-1  activator protein-1  C/EBP  CCAAT/enhancer binding protein  CREB  cyclic AMP response element binding protein  CBP  CREB binding protein  COX-2  cyclooxygenase-2  DMBA  7  12-dimethylbenz[a]anthracene  ERK  extracellular signal-regulated protein kinase  IKK  IκB kinase  JNK  c-Jun-N-terminal kinase  MAP kinase  mitogen-activated protein kinase  NF-κB  nuclear factor-kappaB  PG  prostaglandin  PI3K  phosphoinositide 3-kinase  PKC  protein kinase C  TPA  12-O-tetradecanoylphorbol-13-acetate
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