Delayed Hemolytic Transfusion Reaction in Sickle Cell Disease |
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| Authors: | Leslie P Scheunemann Kenneth I Ataga |
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| Institution: | 1. Immunology Department, Medical Research Institute, Alexandria University, Alexandria, Egypt;2. Hematology Department, Medical Research Institute, Alexandria University, Alexandria, Egypt;3. Clinical Pathology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt;1. Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia;2. Pediatric Immuno-Hematology Unit, Bone Marrow Transplantation Center Tunis, Tunis, Tunisia;3. Information System Directions, Sahloul University Hospital, Sousse, Tunisia;4. National Center of Blood Transfusion, Tunis, Tunisia |
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| Abstract: | Delayed hemolytic transfusion reactions are potentially life-threatening complications observed in patients with sickle cell disease. We review the clinical features, pathophysiology, laboratory evaluation, and management of this complication. It is important that delayed hemolytic transfusion reactions be included in the differential diagnosis of acute pain episodes following a red blood cell transfusion in a patient with sickle cell disease. |
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