| 胸腺免疫抑制提取物对小鼠免疫功能的影响 |
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| 引用本文： | 辛现良,张世玲.胸腺免疫抑制提取物对小鼠免疫功能的影响[J].中国生化药物杂志,1996,17(5):185-187. |
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| 作者姓名： | 辛现良 张世玲 |
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| 作者单位： | 山东医科大学药学系药理教研室!济南250012(辛现良，张世玲)，山东医科大学生化制药教研室(王凤山) |
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| 摘 要： | 研究了猪胸腺免疫抑制提取物对正常及免疫增强小鼠免疫功能的影响。结果表明:本品能抑制正常及免疫增强小鼠的迟发型超敏反应,肌注40mg/kg能抑制正常小鼠溶血素水平,对小鼠碳粒廓清指数及腹腔巨噬细胞吞噬活性均有抑制作用。
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| 关 键 词： | 胸腺免疫抑制提取物 迟发型超敏反应 溶血素 巨噬细胞吞噬 碳粒廓清 |
Effects of Thymic Immunosuppressive Extract on Mouse Immune Functions |
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| Xin Xianliang,Zbang Shiling,Wang FengshanDept of Pharmacology,Facally of Pharmacy,Shandong Medical University.Effects of Thymic Immunosuppressive Extract on Mouse Immune Functions[J].Chinese Journal of Biochemical Pharmaceutics,1996,17(5):185-187. |
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| Authors: | Xin Xianliang Zbang Shiling Wang FengshanDept of Pharmacology Facally of Pharmacy Shandong Medical University |
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| Institution: | Jinan 250012 |
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| Abstract: | Thymic immunosuppressive extract (TIE) prepared from porcine thymus significantly inhibited the delayed type hypersensitivity(DTH) of mouse induced by sheep red blood cells (SRBC). The level of plasma hemolysin was markedly decreased at 40 mg/kg. It had a noticeable suppress! ve effect on the clearance rate of charcoal particles and the activity of macrophage(Mqp). The data indicated that TIE had extensive suppressive effects on mouse immune functions. |
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| Keywords: | Thymic immunosuppressive extract Delayed type hypersensitivity Plasma hemolysin Macrophage phagocytose Clearance rate of charcoal particles |
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