Der Einfluß des Druckes in den Coronararterien auf die Druck-Volumen-Beziehung des linken Ventrikels |
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Authors: | Ph. Greuner-Sigusch G. Greuner C. Morgenstern |
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Affiliation: | (1) Physiologisches Institut der Universität Düsseldorf, Düsseldorf, Deutschland |
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Abstract: | Summary The influence of coronary perfusion pressure on the pressure-volume relation of the left ventricle was investigated in isolated and arrested cat and dog hearts. The left coronary artery was separately perfused.The duration of the experiment, edema of the myocardium and the inflow through the Thebesian vessels complicate the measurement of the pressure-volume relation.Excluding these factors the experiments prove, that coronary perfusion pressure is a determinant of the pressure-volume relation of the heart. Increasing coronary pressure shifts the relation between pressure and volume upward and to the left (Figs. 3 and 4). increases with increasing coronary perfusion pressure, while the elasticity modulus is not changed (Fig. 5). |
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Keywords: | Coronary Perfusion Pressure Pressure-Volume Relation Myocardial Edema Myocardial Stiffness |
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