| 唑类抗真菌药物结构修饰的研发进展 |
| |
| 引用本文： | 王思袭,王峥,蔡正艳,周伟澄. 唑类抗真菌药物结构修饰的研发进展[J]. 中国医药工业杂志, 2007, 38(1): 49-57 |
| |
| 作者姓名： | 王思袭 王峥 蔡正艳 周伟澄 |
| |
| 作者单位： | 上海医药工业研究院,上海,200437 |
| |
| 摘 要： | 唑类药物是治疗真菌感染的主要用药，按化学结构分为咪唑类和三唑类。现综述了唑类药物近年来结构修饰和构效关系的研究进展，为进一步的新药研究提供线索。
|
| 关 键 词： | 三唑 抗真菌 结构修饰 合成 综述 |
| 文章编号： | 1001-8255（2007）01-0049-09 |
| 修稿时间： | 2006-09-11 |
Progress of the Structural Modification on Antifungal Azoles |
| |
| WANG Si-xi,WANG Zheng,CAI Zheng-yan,ZHOU Wei-cheng. Progress of the Structural Modification on Antifungal Azoles[J]. , 2007, 38(1): 49-57 |
| |
| Authors: | WANG Si-xi WANG Zheng CAI Zheng-yan ZHOU Wei-cheng |
| |
| Affiliation: | Shanghai Institute of Pharmaceutical Industry, Shanghai 200437 |
| |
| Abstract: | The azole antifungals including imidazoles and triazoles are the mainstay in clinical treatment of fungal infections. In this paper, their structural modification and structure-activity relationship are reviewed in order to give some clues for the further research. |
| |
| Keywords: | triazoles antifungal structural modification synthesis review |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
