Effect of vincristine of triton WR-1339 induced hyperlipidemia in mice |
| |
| Authors: | T Kremmer L Holczinger |
| |
| Affiliation: | Department of Biochemistry, Oncopathological Research Institute, Budapest, Hungary |
| |
| Abstract: | The effect of Vincristine sulphate on the hyperlipidemia induced in mice by Triton WR-1339 was studied. A single i.p. dose (1 mg/kg) of Vincristine inhibited the development of hyperlipidemia within 2–4 hr. Vincristine sulphate seems to exert its lipid lowering effect through the liver by inhibiting either the synthesis or the excretion of lipoproteins or both. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
