溶栓治疗75岁以上老年急性心肌梗死患者的疗效观察

目的观察尿激酶静脉溶栓治疗75岁以上老年急性心肌梗死患者的临床疗效。方法75岁以上老年急性心肌梗死患者75例，溶栓组35例，对照组（未溶栓组）40例，溶栓组采用尿激酶及心肌梗死常规治疗方法，对照组除不用尿激酶外其他治疗方法相同。结果溶栓组临床血管再通率62．86％，病死率11．43％，无严重并发症。对照组的临床血管再通率22．5％，病死率27．5％。结论尿激酶静脉溶栓治疗75岁以上老年急性心肌梗死患者可提高再通率降低死亡率，减少并发症，改善预后。

The efficacy of thrombolysis on acute myocardial infarction(AMI) in elder patients over 75 years old

Objective To observe the efficacy of intravenous thrombolysis with urokinase in patients with acute myocardial infarction（AMI） aged over 75 years. Methods Seventy - five patients with AMI aged over75 years were divided into two groups ： thrombolytic therapy group （ n = 35 ） and control group （ n = 40 ） with conventional treatment. Patients in thrombolyfic therapy group were treated with combined therapy of intravenous administration of urokinase and conventional medicines, and patients in control group were only treated with conventional medicines. Result The clinical recanalization rate in patients of thrombolytic therapy group was 62.86% , while the mortality was 11.43 % and no serious hemorrhagic complications occurred in these patients. The clinical recanalization rate in patients of control group was 22.5% , while the mortality was 27.5%. Conclusion The intravenous thrombolysis with urokinase can decrease the mortality and improve the prognosis of patients with AMI aged over 75 years.