Morphological and molecular characteristics of living human fetuses between Carnegie stages 7 and 23: ultrasound scanning and direct measurements |
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| Authors: | Harkness LM; Rodger M; Baird DT |
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| Institution: | Department of Obstetrics and Gynaecology, University of Edinburgh, 37 Chalmers Street, Edinburgh EH3 9EW, UK
0 Corresponding author |
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| Abstract: | The developmental age of an embryo in the first trimester ofpregnancy is generally determined by ultrasound scanning and/orby calculation from menstrual age. In the original studies,validation of the estimate of gestational age by ultrasoundwas not possible as the exact date of conception was unknown.Variation in growth rates of identically aged fetuses has previouslybeen reported after assisted conception and with the use ofultrasound scanning. As these pregnancies were ongoing the accuracyof the scanning results could not be determined. Comparisonof scanning and direct measurements after termination of pregnancyand menstrual age were carried out to determine the accuracyin fetal dating. The results suggest that the use of ultrasoundscanning to determine gestational age is of less use than previouslythought, and that the use of menstrual age is severely limited. |
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| Keywords: | crown-rump length/embryo/gestational age/menstrualage/ultrasound |
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