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Case of fulminant leptospirosis in a renal transplant patient |
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| Authors: | L. Gerasymchuk A. Swami C.F. Carpenter D. Samarapungavan M. Batke R. Kanhere B. Robinson-Dunn J.D. Wilson J. Szela |
| Affiliation: | Department of Medicine, Division of Infectious Diseases, William Beaumont Hospital, Royal Oak, Michigan, USA;, Department of Medicine, Division of Nephrology, William Beaumont Hospital, Royal Oak, Michigan, USA;, Department of Medicine, Division of Gastroenterology, William Beaumont Hospital, Royal Oak, Michigan, USA;, Department of Pathology, Division of Clinical Pathology, William Beaumont Hospital, Royal Oak, Michigan, USA;and Department of Pathology, Division of Clinical Microbiology, William Beaumont Hospital, Royal Oak, Michigan, USA |
| Abstract: | Abstract: We present a case of fulminant leptospirosis that was acquired in the suburban area by a 48-year-old male renal transplant recipient. He developed acute renal and hepatic failure with profound jaundice. Spirochetes were identified on liver biopsy. Weil's disease was suspected, and the diagnosis was further supported by a positive serum Leptospira interrogans icterohaemorrhagiae antibody titer. Unfortunately, he suffered from recurrent lower gastrointestinal bleeding, had a prolonged hospital course, and eventually succumbed to overwhelming sepsis. This case is the third report to our knowledge of leptospirosis in a renal transplant recipient in the English literature. |
| Keywords: | leptospirosis spirochete renal transplant immunosuppression hepatic failure renal failure zoonosis |