多囊卵巢综合征患者糖耐量及胰岛素水平的意义探讨

目的：探讨多囊卵巢综合征（PCOS）患者糖代谢和胰岛素释放的临床意义。方法：检测分析56例PCOs患者组和60例对照组的糖耐量及胰岛素水平。结果：体重指数（BMI）〈25的PCOS患者空腹和口服葡萄糖后1小时、2小和3小时的血糖水平与对照组无显著性差异（P〉0．05），胰岛素水平均显著高于对照（P〈0．05）。BMI〉25的PCOS患者空腹及口服葡萄糖后1小时、2小时和3小时的血糖和胰岛素水平均显著高于对照组和BMI〈25的PCOS患者（P〈0．05）。结论：肥胖PCOS患者更易出现糖代谢异常，肥胖可能加重糖代谢异常和胰岛素抵抗。动态检测糖耐量及胰岛素水平可指导PCOS患者的治疗。

Exploration of Clinical Significance of Glucose Tolerance and Insulin Level in Patients with Polycystic Ovary Syndrome

Objective： To investigate the clinical significance of glucose metabolism and insulin release levels in the women with polycystic ovary syndrome （PCOS）. Methods： Glucose tolerance and insulin levels were compared between 56 patients with PCOS and 60 healthy women served as controls. Results： There were not significant differences between patients with PCOS with MBI〈25 and control group in serum glucose levels within0h, lh, 2h and 3h after oral glucose （P〉0. 05）, serum insulin levels in patients with PCOS with BMI〈25 were higher than control group （P〈0. 05）. Serum glucose and insulin levels in patients with PCOS with BMI〉25 were higher than PCOS w.ith MBI〈25 and control group within Oh, lh, 2h and 3h after oral glucose （P〈0.05）. Conclusion： Glucose metabolic abnormality and insulin resistance were developed more easily in patients with PCOS with BMI〉25. Obesity may exacerbate insulin resistance, determination of glucose tolerance and insulin levels can be used to guide treatment of patients with PCOS.