利伐沙班与华法林治疗非瓣膜性心房颤动的对比效果分析

目的:分析利伐沙班与华法林治疗非瓣膜性心房颤动的对比效果。方法:选取本院2017年10月—2018年9月收治的150例非瓣膜性心房颤动患者作为研究对象,借助双盲随机抽样法分为对照组和观察组,每组75例。对照组给予华法林治疗,观察组予以利伐沙班治疗,评定两组治疗效果、栓塞事件发生情况与肝功能指标。结果:治疗前,两组肝功能指标无显著差异,P>0.05;治疗后,观察组相比对照组的肝功能指标改善显著,P<0.05。观察组(97.33%,73/75)相较于对照组(82.67%,62/75)治疗效果较高;观察组(1.33%,1/75)相较于对照组的栓塞事件发生率(13.33%,10/75)较低,P<0.05。结论:非瓣膜性心房颤动予以利伐沙班治疗效果十分显著,在易于提升治疗效果的同时降低栓塞事件发生率,值得临床进一步深究与采纳。

Comparison of rivaroxaban and warfarin in the treatment of nonvalvular atrial fibrillation

Objective:To analyze the comparative effect of rivaroxaban and warfarin in the treatment of non-valvular atrial fibrillation.Methods:A total of 150 patients with non-valvular atrial fibrillation who were treated in our hospital from October 2017 to September 2018 were selected as the research subjects.They were divided into a control group and an observation group by double-blind random sampling,with 75 cases in each group.The control group was treated with warfarin,and the observation group was treated with rivaroxaban.The therapeutic effects,embolization events,and liver function indexes of the two groups were evaluated.Results:Before treatment,the liver function indexes of the two groups were not significantly different,P>0.05;after treatment,the liver function indexes of the observation group were significantly improved compared with the control group patients,P<0.05.The observation group(97.33%,73/75)had a higher treatment effect than the control group(82.67%,62/75);the observation group(1.33%,1/75)had a lower incidence of embolic events(13.33%,10/75)compared with the control group,P<0.05.Conclusion:Rivaroxaban is very effective for patients with nonvalvular atrial fibrillation.It is easy to improve the treatment effect and reduce the incidence of embolic events.It is worthy of further clinical study and adoption.