腹腔镜直肠癌根治术对患者血清C反应蛋白的影响

目的:探讨腹腔镜直肠癌手术对患者血清C反应蛋白(CRP)的影响.方法:70例患者随机分为腹腔镜直肠癌根治术(腹腔镜组)和开腹直肠癌根治术(开腹组),术前1 d和术后1、3、5、7 d采用酶联免疫吸附双抗体夹心(ELISA)法测定血清中CRP水平,观察术中出血量、淋巴结数、肠动力恢复时间及手术并发症等情况.结果:腹腔镜组...

Change of C-reactive protein in patients with colorectal cancer treated by laparoscopic radical operation

Objective： To investigate the effects of laparoscopic radical operation on C-reactive protein（CRP） in patients with colorectal cancer.Methods： A total of 70 patients with colorectal cancer were divided into laparoscopic radical operation（laparoscope group） and conventional open radical operation（laparotomy group）.The serum CRP was detected by ELISA on 1st day before surgery and 1st,3th,4th,7th day after surgery.The blood loss,number of lymph nodes,gastrointestinal motility recovery time and complications were observed.Results： The blood loss,postoperative complication and gastrointestinal motility recovery time were significantly lower than those of laparotomy group,and differences between two groups were significant（P〈0.05）.There were no positive surgical margins in the two groups,and no significant difference in number of lymph nodes between two groups（P〉 0.05）.On the 1st day before surgery,there was no significant difference in CRP level（P〉 0.05）,but on the 1st,3th,4th,7th day after surgery,the CRP level of laparotomy group was significantly higher than the laparoscope group（P〈0.05）.Conclusion： The laparoscopic radical operation on the body with colorectal cancer has fewer traumas.The acute inflammatory response is mild and good for postoperative recovery.