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2687例血清甲状腺球蛋白抗体和微粒体抗体测定及其临床意义
引用本文:包荫堂,吴观钦,姚薇萱. 2687例血清甲状腺球蛋白抗体和微粒体抗体测定及其临床意义[J]. 南京医科大学学报(自然科学版), 1988, 0(2)
作者姓名:包荫堂  吴观钦  姚薇萱
作者单位:南京医学院第一附属医院核医学科(包荫堂,吴观钦),南京医学院第一附属医院核医学科(姚薇萱)
摘    要:报告2687例血清甲状腺球蛋白抗体和甲状腺微粒体抗体的放射免疫测定结果,九类病人的抗体阳性率如下:甲状腺正常病人12.6(30/239)、孤立甲状腺结节16.9%(62/383)、弥漫性甲状腺肿35.4%(226/638)、多结节甲状腺肿54.7%(104/190)、甲亢未治疗77.7%(404/520)、甲亢治疗中67.2%(218/345)甲亢临床已治愈60.3(102/169),原发性甲减80.8%(118/146)、亚急性甲状腺炎35.1%(20/57)。各种甲状腺疾病的总阳性率为51.2%(1254/2448)。对甲状腺自抗体阳性在甲状腺疾病的诊断、治疗、和预后判断上的意义进行了讨论。

关 键 词:甲状腺疾病  甲状腺球蛋白抗体  甲状腺微粒体抗体  放射免疫测定  人类

RESULTS OF SERUM THYROGLOBULIN ANTIBODY AND THYROID MICROSOMAL ANTIBODY MEASUREMENT OF 2687 PATIENTS AND ITS CLINICAL SIGNIFICANCE
Bao Yintang,et al.. RESULTS OF SERUM THYROGLOBULIN ANTIBODY AND THYROID MICROSOMAL ANTIBODY MEASUREMENT OF 2687 PATIENTS AND ITS CLINICAL SIGNIFICANCE[J]. Acta Universitatis Medicinalis Nanjing, 1988, 0(2)
Authors:Bao Yintang  et al.
Abstract:Serum thyroglobulin antibody and thyroid microsomal antibody weremeasured by radioimmunoassay from 2687 patients with 9 kinds of disea-ses.The frequency of positive responces were:12.6%(30/239)of patientswith normal thyroid,16.9%(62/383)of solitary thyroid node,35.4%(226/638)of diffuse goiter,54.7%(104/190)of multiple node goiter,7.77%(404/590)of untreated patients with hyperthyroidism,67.2%(218/345)of patients of hyperthyroidism during treatment,60.3%(102/169)of re-covered patients of hyperthyroidism,80.8%(118/146)of primary hypothy-roidism and 35.1%(20/57)of subacute thyroiditis respectively.The totalfrequency of positive response was 51.2%(1254/2448).The tests play asignificant role in diagnosis,treatment and prognsis of thyroid diseases.
Keywords:thyroid diseases  thyroglobulin antibody  thyroid microsomal antibody  radioimmunaoassay  human
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