肠系膜下动脉在晚期卵巢癌及其术后复发介入治疗中的价值

目的 探讨肠系膜下动脉在晚期卵巢癌及其术后复发患者介入治疗中的价值.方法 对34例晚期卵巢癌及术后复发患者(其中晚期22例,术后复发12例)在行常规双侧髂内动脉和(或)子宫动脉化疗和(或)栓塞后,对肠系膜下动脉参与供血者行灌注化疗,并观察其疗效.结果 本组病例中,共有26例肠系膜下动脉参与肿瘤供血.灌注化疗后3周随访CT见肿块皆有不同程度缩小.1例另行栓塞治疗,未出现肠坏死等并发症;其中卵巢癌术后复发者肠系膜下动脉有异常供血占90.9%(20/22),而晚期者则占50.0%(6/12),2组间差异有统计学意义(X2=7.2,P=0.007);卵巢癌FIGO分期Ⅲ期占61.5%(8/13),Ⅳ期占85.7%(18/21),2组间差异无统计学意义(X2=2.608,P=0.16).结论 在晚期卵巢癌,尤其是术后复发患者的血管内介入治疗中,肠系膜下动脉常参与肿瘤的血供,故常规仅行双侧髂内动脉和(或)子宫动脉介人治疗往往疗效不佳.因此对此类患者行血管内介入治疗时,常规探查肠系膜下动脉并进行灌注化疗,具有重要的临床价值.

The significance of inferior mesenteric artery in the interventional treatment for unresectable and recurrent ovarian carcinoma

Objective To discuss the significance of inferior mesenteric artery (IMA) in the interventional treatment for unresectable and recurrent ovarian carcinoma. Methods Thirty-four patients with ovarian carcinoma, including unresectable advanced cases (n = 22) and post operative recurrent cases (n = 12), underwent routine interventional arterial chemotherapy and / or embolization via bilateral internal iliac arteries and / or uterine arteries. Infusion chemotherapy through IMA was carried out if IMA was involved...