中药降压汤合倍他乐克治疗高血压病疗效观察

目的:研究降压汤合小剂量倍他乐克治疗肝阳上亢型原发性高血压(EHT)的疗效。方法:将80例肝阳上亢型EHT患者随机分为A,B,C,D 4组,每组20例,A组服用降压汤,B组服用小剂量倍他乐克,C组服用上述2种药物,D组服用大剂量倍他乐克。用药4周后,比较4组血压、血脂、心率的变化。结果:中药组患者的血压较治疗前低(P<0.05),甘油三酯(TG)降低(P<0.01),胆固醇(TC)降低(P<0.01),而心率无明显变化(P>0.05);小剂量西药组患者心率较治疗前低(P<0.05),而血压、血脂无明显变化(P>0.05);中西药组患者血压、血脂、心率得以理想控制;大剂量西药组血压、心率较治疗前低(P<0.05),而甘油三酯(TG)升高(P<0.05),高密度脂蛋白(HDL-C)降低(P<0.05)。结论:降压汤与小剂量倍他乐克联合用药治疗肝阳上亢型EHT是有效的。

Jiangya Decoction and Betaloc in Essential Hypertension Treatment

Objective:To search for the therapeutic effect of Jiangya Decoction and betaloc for treating essential hypertension(EHT) of types of the liver hyperactivity of yang.Methods:The 80 cases were divided into four groups randomly:group A,group B,group C and group D.Each group included 20 cases.Group A was treated with Jiangya Decoction;group B with a little dosage betaloc;group C with Jiangya Decoction and a little dosage betaloc;and group D with much betaloc.After 4 weeks,the changes of blood pressure(BP),blood lipid and heart rate were observed.The results were analyzed with statistics.Results:The levels of BP in the group A was lower than previous to treatment(P<0.05) and TG,TC were lower(P<0.01),and in the group,no changes of heart rat was observed(P>0.05).In the group B,no significant changes in BP and blood lipid were observed and the heart rat was lower than previous to treatment(P<0.05).In the group C,the ideal control for BP,blood lipid and heart rat were found.In the group D,the levels of BP and heart rat were lower than previous to treatment(P<0.05),but the levels of TG were higher and HDL-C were lower than previous to treatment(P<0.05).Conclusion:In the ideal control for BP,blood lipid and heart rat,we can find that the treatment of combining Jiangya Decoction with a little betaloc for EHT belonged to the types of the liver hyperactivity of yang is effective,and the study provides objective data for EHT in therapy.