| 口服决明子后血清及尿液中的蒽醌类分析 |
| |
| 引用本文： | 李续娥,马伟,郭宝江,曾志. 口服决明子后血清及尿液中的蒽醌类分析[J]. 中国中药杂志, 2003, 28(9): 849-851 |
| |
| 作者姓名： | 李续娥 马伟 郭宝江 曾志 |
| |
| 作者单位： | 1. 华南师范大学,生命科学学院,广东,广州,510631
2. 广州中医药大学,广东,广州,510405 |
| |
| 基金项目： | 广东省科技计划项目 (C 30 1 1 3) |
| |
| 摘 要： | 目的 :分析不同动物 (人 )口服决明子后吸收入血的蒽醌类。方法 :用HPLC法对口服决明子后的大鼠血清和尿液、健康人尿液中的结合蒽醌和游离蒽醌进行测定。结果 :大鼠和人对决明子粉及其煎液中的蒽醌类只能部分吸收入血 ,且所吸收的蒽醌种类存在差异 ;在决明子蒽醌类的吸收及代谢过程中 ,有新物质产生。结论 :决明子蒽醌类活性成分的进一步筛选应以所研究的动物 (人 )吸收入血的蒽醌类为切入点。
|
| 关 键 词： | 决明子 蒽醌类 血清 尿液 |
| 文章编号： | 1001-5302(2003)09-0849-03 |
| 收稿时间： | 2002-11-12 |
| 修稿时间： | 2002-11-12 |
Analysis of Anthraquinones in Serum and Urine after Oral Adm inistration of Semen Cassiae |
| |
| LI Xu-e ;MA Wei ;GUO Bao-jiang ;ZENG Zhi. Analysis of Anthraquinones in Serum and Urine after Oral Adm inistration of Semen Cassiae[J]. China Journal of Chinese Materia Medica, 2003, 28(9): 849-851 |
| |
| Authors: | LI Xu-e MA Wei GUO Bao-jiang ZENG Zhi |
| |
| Affiliation: | College of Life Science of South China Normal University, Guangzhou 510631, Guangdong, China. lixue@scnu.edu.cn |
| |
| Abstract: | Objective: To analysie the anthraquinones a bsorbed into serum by different animals (or human beings)after oral administra tion of Semen Cassiae. Method: Anthraquinones in serum an d urine of rats and urine of healthy men after taking Semen Cassiae orally were detected with HPLC. Result: Only some of the anthraquinon es were absorbed into serum. There were differences in absorption and metabolism of anthraquinones between rats and men and some new anthraquinones were produce d in the process. Conclusion: Anthraquinones absorbed into serum by the experimental animals or men should become target for researching i nto active compounds of anthraquinones in Semen Cassiae. |
| |
| Keywords: | Semen Cassiae anthraquinones serum urine |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
