Evaluation of gastrointestinal hemorrhage in patients with neurofibromatosis |
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Authors: | I. A. Mustafa W. P. Reed N. P. W. Coe |
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Affiliation: | (1) Department of Surgery, Tufts University School of Medicine, and Baystate Medical Center, 759 Chestnut Street, 01199 Springfield, MA, USA |
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Abstract: | Over a 3-year period, two patients with neurofibromatosis were referred to our medical center for evaluation of repeated episodes of melena. Upper endoscopy was unrevealing in each case, as was colonoscopy. Arteriography during active hemorrhage was helpful in localizing the source of bleeding in one patient but not in the other. The source of bleeding in each patient was obvious at surgical exploration. Large neurofibromas protruded from the seorsal surface of a short region of jejunum in both cases and an additional segment of ileum in one case. Hemorrhage had occurred as a result of erosion of mucosa stretched over these tumors. Local resection of the involved segments produced long-term control of the hemorrhage. Since these tumors were grossly visible on the serosal surface of the involved intestinal segments, laparoscopic evaluation could have been used to hasten diagnosis in each case. |
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Keywords: | Neurofibromatosis Gastrointestinal hemorrhage |
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