Construction of comparative cytogenetic maps of the Chinese hamster to mouse, rat and human |
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| Authors: | Asato Kuroiwa Kimiyuki Tsuchiya Kazumi Matsubara Takao Namikawa Yoichi Matsuda |
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| Affiliation: | (1) Laboratory of Cytogenetics, Division of Bioscience, Graduate School of Environmental Earth Science, Hokkaido University, North 10, West 8, Kita-ku, Sapporo 060-0810, Japan;(2) Laboratory of Animal Genetics, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan;(3) Experimental Animal Center, Miyazaki Medical College, 5200 Kihara, Kiyotake-cho, Miyazaki 889-1601, Japan;(4) Chromosome Research Unit, Faculty of Science, Hokkaido University, North 10, West 8, Kita-ku, Sapporo 060-0810, Japan |
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| Abstract: | We constructed comparative cytogenetic maps of the Chinese hamster to mouse, rat and human by fluorescence in-situ hybridization using 36 cDNA clones of mouse, rat, Syrian hamster, Chinese hamster and human functional genes. In this study, 30 out of the 36 genes were newly mapped to Chinese hamster chromosomes. The chromosomal homology of the Chinese hamster was identified and arranged in 19, 19 and 18 segments of conserved synteny in mouse, rat and human, respectively. Additionally, two of the 19 segments homologous to mouse chromosomes were initially identified in this study. This revised version was published online in July 2006 with corrections to the Cover Date. |
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| Keywords: | Chinese hamster comparative map FISH |
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