| 妊娠相关蛋白A与高敏C反应蛋白在不稳定心绞痛患者血清中的表达及临床意义 |
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| 引用本文： | 翁建新,刘东,方伟,王正瑛,罗建方,张敏洲.妊娠相关蛋白A与高敏C反应蛋白在不稳定心绞痛患者血清中的表达及临床意义[J].海南医学,2006,17(10):32-33. |
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| 作者姓名： | 翁建新 刘东 方伟 王正瑛 罗建方 张敏洲 |
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| 作者单位： | 广东省深圳市宝安区西乡人民医院,广东,深圳,518102;广东省人民医院;广东省中医院 |
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| 摘 要： | 目的 检测妊娠相关蛋白A和hs-CRP在不稳定心绞痛患者的血清表达水平.方法 将病人分为三组,分别为不稳定型心绞痛组(n=30例),稳定型心绞痛组(n=28例),正常对照组(n=20例),全部患者均采用酶联免疫吸附法(Elisa)测定血清PAPP-A和超敏免疫透射比浊法测血浆hs-CRP的浓度.结果 在UAP患者中,血清PAPP-A和hs-CRP水平明显高于SAP及正常人水平(P＜0.01).结论 PAPP-A及高敏CRP在血液中的水平与冠心病的严重程度有密切相关,提示两者均可作为预测不稳定心绞痛预后的新的敏感的标志物.
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| 关 键 词： | 不稳定型心绞痛 妊娠相关蛋白A(PAPP-A) 高敏CRP(hs-CRP) |
| 文章编号： | 1003-6350（2006）10-032-02 |
The expression and clinical significance of Pregnanly Associated Plasma Protein-A (PAPP-A) High-sensitnity C-Reactive protein (hs-CRP) in the serum of patient with unstable Angina |
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| WENG jian-xin,LIU dong,FANG Wei,WANG Zheng-ying,LUO Jian-fang,ZHANG Min-zhou.The expression and clinical significance of Pregnanly Associated Plasma Protein-A (PAPP-A) High-sensitnity C-Reactive protein (hs-CRP) in the serum of patient with unstable Angina[J].Hainan Medical Journal,2006,17(10):32-33. |
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| Authors: | WENG jian-xin LIU dong FANG Wei WANG Zheng-ying LUO Jian-fang ZHANG Min-zhou |
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| Abstract: | Objective To explore the expression of PAPP-A? hs-CRP in the serum of the patients with anstable Angina. Methods Divide three groups: UAP group (n=30) SAP group (n=28) Normal healthy group (n=20). All the patients were analysed for PAPP-A and hs-CRP with enzyme-linkedimm unosorbent (ELISA) and untrasensitive immunoassy respectively. Results The plasma PAPP-A, hs-CRP levels in the patients with UAP in creased significantly higher, compare with those in SAP and Normal health group (P<0.01). Conclusions the level of PAPP- A? hs-CRP are positive correlation with UAP, and can be a nearly sensitive for the patients with UAP. |
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| Keywords: | Unstable Angina Pregnancy-Associated Plasma protein A High-sensitivity C-Reactive protein |
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