内镜下金属支架置入术联合放疗治疗中晚期食管癌

目的 观察与评价内镜下带膜金属支架置入术联合放射治疗（放疗）治疗中晚期食管癌的临床可行性及疗效。方法 对18和16例中晚期食管癌病人分别行内镜下带膜金属支架置入术和支架联合放疗。观察CES型不锈钢金属支架对放疗射线分布的影响、比较单纯支架治疗和联合放射治疗病人的生存率、临床症状缓解率及并发症发生率。结果 ①CES型不锈刚金属支架对放疗射线分布无影响；②单纯支架组与联合治疗组病人在吞咽困难症状缓解及并发症发生率方面无差别；③联合治疗组病人的6、9、12个月的生存率明显高于单纯支架组。结论 内镜下金属支架置入联合放疗是治疗中晚期食管癌的可行方法，其临床疗效明显优于单纯支架置入术。

Treatment of medium and late stages of esophageal carcinomas with combination of endoscopic metal stenting and radiotherapy

Objective To observe and evaluate clinical feasibility and efficacy of endoscopic metal stenting and combined radiotherapy in treatment of medium and late stages of esophageal carcinoma. Methods 34 cases of medium and late stages of esophageal carcin oma were treated with endoscopic stent implantation and in combination with sten t and radiotherapy. Evaluation of CES stainless metal stent on rad iation effect, clinical symptom alleviation and complication rates and survival rates in both groups was made. Results 1) CES stainless stent had no effect on radiation dosage distribution; 2) Dysphagia was markedly alleviated in both groups and no differe nce in complication rates was observed between two groups; 3) The survival rates of 6,9,12 months in patients treated with combined therapies were significantly higher than those in simple stent implantation patients. Conclusions Endoscopic metal stenting in combination with radiothe rapy was a feasible and practical management in treating medium and late stages of esophageal carcinoma, which was superior to simple metal stent implantation.