深圳东部地区无偿献血人群中HIV感染者特征及蛋白质免疫印迹带型分析

目的 掌握深圳东部地区无偿献血人群中HIV感染者人口学特征及蛋白质免疫印迹(WB)带型,为献血者招募、员工职业防护和血液检测提供理论依据.方法 收集2010-2019年深圳东部地区无偿献血人群经WB法确认的62例HIV感染者资料,采用x2检验比较各年度感染率;对HIV感染者的性别、年龄、户籍、职业、文化程度、婚姻状况构...

Analysis on the characteristics and Western blotting band patterns of voluntary blood donors with HIV infection in Eastern area of Shenzhen

Objective To learn the demographic characteristics and Western blotting(WB)band patterns of HIV infection patients among voluntary blood donors in Eastern area of Shenzhen,so as to provide theoretical basis for recruitment of blood donors,occupational protection of our staffs and blood testing.Methods A total of 62 HIV-infected individuals who were confirmed by WB from voluntary blood donors in Eastern area of Shenzhen from 2010 to 2019 were collected,and the differences on infection rates were compared by usingχ² tests.Descriptive epidemiological method was used for composition ratio analysis on sex,age,household registration,occupation,education,and marital status.WB band positive rates and band patterns were analyzed separately.Results The total HIV infection rate of voluntary blood donors in Eastern area of Shenzhen from 2010 to 2019 was 3.92.The differences on HIV infection rates among blood donors in each year were statistically significant(χ²=29.44,P<0.05).The infection rate of blood collection site A in the year of 2019 was 12.45 and the total infection rate of the others was 1.81,the difference of these was statistically significant(χ²=5.88,P<0.05).Among the 62 HIV-infected donors,93.55%were male,74.20%with the age of 18—<36,61.29%were unmarried,93.55%were non-Shenzhen household registration,43.55%were business services and 32.26%were workers,88.71%were high-middle school or less educated.A total of 4 kinds of WB band patterns were the main bands.The bands of gp160,gp120,p66,p24 were observed in all the patients(100.00%),the bands of p17 and p55 showed low positive rates(67.74%and 51.61%respectively).Conclusion The majority of HIV-infected voluntary blood donors in Eastern area of Shenzhen are in early or middle infected stage,18—<36 years old,unmarried,non-Shenzhen household registration,business services or workers,high-middle school or less educated,and we should pay more attention to the voluntary blood donors of the blood collection site A.