脑外伤真菌感染的临床分析

目的 探讨医院脑外科真菌感染的临床特点。方法 分析本院2003年3月至2007年3月840例脑外伤患者真菌感染的临床资料。结果 840例患者感染真菌176例，占20．9％，共分离到病原性真菌205株，其中白色念珠菌94例，占45．9％，热带念珠菌57例，占27．8％，近平滑念珠菌20例，占9．8％，光滑球拟酵母菌13例，占6．3％。新型隐球菌6例，占2．9％，其他11例，占5．4％。结论 近年来医院真菌感染的发病率明显增高，白色念珠菌最常见，均表现出一定程度的耐药。

Clinical analysis about fungous infection during cerebral trauma

Objective To discuss clinical feature about fungous infection during cerebral trauma in hospital. Methods Clinical data about 840 cases with cerebral trauma from Mar 2003 to Mar 2007 in our hospital were collected and analyzed for fungous infection. Results The infection rate was 20.9% （176/840）. A total of 205 strains of pathogenic mycetes were isolated, in which Endomyces albicans accounted for 45.9 % （94/205）, Candida parapsilosis 9.8 % （20/205）, Torulopsis glabrata 6.3% （13/205）, Cryptococcus hominis 2.9 % （6/205）, and other mycetes ,5.4% （11/205）. Conclusion In recent years, incidence of mycete infection increases obviously, and Endomyces albicans is the most common, resistant to antifungal agents to a certain degree.