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甘草酸二铵肠溶胶囊治疗药物性肝损害的疗效观察
引用本文:李剑鹏,黄俊,甘楚林,钟大明. 甘草酸二铵肠溶胶囊治疗药物性肝损害的疗效观察[J]. 中国医药导刊, 2011, 13(11): 1904-1905
作者姓名:李剑鹏  黄俊  甘楚林  钟大明
作者单位:1. 广西梧州市第三人民医院肺科,梧州,543002
2. 广西梧州市第三人民医院门急诊科,梧州,543002
3. 广西梧州市第三人民医院肝科,梧州,543002
摘    要:目的:观察甘草酸二铵肠溶胶囊治疗抗结核药物所致的肝损害的临床疗效。方法:将我院近年来收治的77例符合使用抗结核药物所致肝损害的患者随机分为治疗组和对照组,分别给予甘草酸二铵肠溶胶囊和甘草酸二铵胶囊进行护肝治疗,对其疗效进行统计学分析比较。结果:治疗组肝功能恢复情况明显优于对照组(P<0.05)。结论:应用甘草酸二铵肠溶胶囊治疗抗结核药物所致肝损害疗效显著。

关 键 词:甘草酸二铵肠溶胶囊  抗结核药物  药物性肝损害

The Efficacy of Diammonium Glycyrrhizinate Enteric-coated Capsules in Treating Liver Damage Caused by Anti-tuberculosis Drugs
Affiliation:Li Jian peng1,Huang Jun2,Gan Chu-lin3,et al (1 The Respiratory Department,2 Emergency Department,3 Liver Department,the Third People’s Hospital of Wuzhou,Wuzhou 543002,China)
Abstract:Objective:To investigate the efficacy of diammonium glycyrrhizinate enteric-coated capsules in treating liver damage caused by anti-tuberculosis drugs.Methods:77 patients with liver damage caused by anti-taberculosis in our hospital were divided into two groups at random.Patients in test group received diammonium glycyrrhizinate enteric-coated capsules.Patients in control group received diammonium glycyrrbizinate capsuies.The therapeutic outcome were compared between two groups by statistical test.Results:In test group,the improvement of liver function was obviously better man that of control group(P<0.05).Conclusion:Diammonium glycyrrbizinate enteric-coated capsules is an effective medicine in treating liver damage caused by anti-tuberculosis drugs.
Keywords:Diammonium glycyrrhizinate enteric-coated capsules  Anti-tuberculosis drugs  Drug-induced liver damage
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