| 血小板相关抗体检测在血小板减少症中的临床意义 |
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| 引用本文： | 顿晓熠,哈力达·亚森,马艳,郭新红. 血小板相关抗体检测在血小板减少症中的临床意义[J]. 新疆医科大学学报, 2007, 30(1): 64-65,68 |
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| 作者姓名： | 顿晓熠 哈力达·亚森 马艳 郭新红 |
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| 作者单位： | 新疆医科大学第一附属医院血液科,新疆,乌鲁木齐,830054 |
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| 摘 要： | 目的：探讨血小板相关抗体（PAIg）检测在血小板减少症中的l临床意义。方法：选择110例血小板减少症患者及10例外周血系均在正常范围的健康体检者（正常对照组），采用ELSIA法进行PAIgG、PAIgA、PAIgM3项联合检测。结果：特发性血小板减少性紫癜（ITP）、再生障碍性贫血（AA）、骨髓增生异常综合征（MDS）、血液系统肿瘤、肝病患者PAIg阳性率均明显高于正常对照组。ITP、AA、血液肿瘤组及肝病组患者的PAIgG、PAIgA、PAIgM值均高于正常对照组，差异有统计学意义（P〈0．05）。结论：PAIg的检测有助于了解血小板减少症的发生机制。
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| 关 键 词： | 血小板相关抗体(PAIg) 检测 血小板减少症 |
| 文章编号： | 1009-5551（2007）01-0064-03 |
| 收稿时间： | 2006-02-16 |
| 修稿时间： | 2006-02-16 |
The clinical significance of platelet-associated immunoglobulin examination for thrombocytopenia |
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| Abstract: | Objective: To investigate the clinical significance of platelet-associated immunoglobulin (PAIg) examination for thrombocytopenia. Methods: The level of PAIgG, PAIgA and PAIgM were detected in 110 patients with thrombocytopenia and 10 normal volunteers as control group by ELSIA. Results: The positive rates of PAIg in patients with ITP, AA, MDS, hematology tumor and liver disease were significantly higher than that in normal controls. Conclusion: Test of PAIg is helpful to know the etiopathological mechanism of thrombocytopenia. |
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| Keywords: | platelet-associated immunoglobulin(PAIg) examination thrombocytopenia |
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