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原发性肝癌死亡病例年龄和性别及严重并发症分布规律分析
引用本文:韩聚强,骆利,任永强,王帅,李国安,闻炜,曹建彪.原发性肝癌死亡病例年龄和性别及严重并发症分布规律分析[J].中国医学装备,2013(2):5-7.
作者姓名:韩聚强  骆利  任永强  王帅  李国安  闻炜  曹建彪
作者单位:[1]北京军区总医院全军肝病治疗中心,北京100700 [2]北京军区总医院心理科,北京100700
基金项目:国家自然科学基金(30972594)“雌激素受体信号通路调控肝纤维化发生的一种新型共调节因子”;国家自然科学基金(30571655)“乙型肝炎病毒X蛋白诱发肝癌发生的一条新型信号通路”;中国肝炎防治基金会王宝恩肝纤维化研究基金(2010-14)“结缔组织因子调控肝纤维化发生的一条新型信号通路”
摘    要:目的:通过分析原发性肝癌死亡病例,探讨合并各种并发症的分布规律及相关因素。方法:选取253份原发性肝癌死亡病例进行回顾性流行病学调查及相应分层分析。结果:原发性肝癌死亡病例中男、女患者性别比列为5:1,其中死亡年龄男性患者偏低,女性患者在60岁以上;年龄因素与各并发症构成比有显著统计学意义,其中〈40岁死亡病例中肝癌破裂出血所占比例较其他各组比例显著增高,而肝性脑病病例较其他各组病例数明显较低;40~49岁死亡病例中合并其他脏器转移的病例所占比例较其他病例较高;〉80岁老年死亡病例中合并肝炎、肝硬化死亡病例明显较少,而肺部感染及呼吸衰竭病例较其他各组明显增高。结论:原发性肝癌死亡病例中各并发症构成与年龄、性别密切相关。

关 键 词:原发性肝癌  并发症  死亡病例  分层分析

An analysis of statistic stratification on the severe complications of primary hepatocellular carcinoma
Institution:HAN Ju-qiang, LUO Li, REN Yong-qiang, et al Department of Liver Diseases, General Hospital of Beijing Command, Beijing 100700, China.
Abstract:Objective: To investigate the distributing feature of the severe complications of primary hepatocellular carcinoma(HCC) as well as the relative factors in 253 died HCC cases. Methods: An analysis of statistic stratification was made in 253 died cases of primary hepatocellular carcinoma (HCC), who were treated in our department, from 1999 to 2009. Results: The gender ratio was 5:1 between the male and the female in all 253 cases. The female age of death was significantly higher than the male ones. By the analysis of stratified statistics~ there was significant relation I~etween age of death and the constituent ratio of severe complication in 255 died HCC cases. The hemorrhage of HCC happened frequently in the cases less than 40 years old. On the contrary, the elder cases more than 80 years had the higher prevalence of lung infection as well as respiratory failure among the severe complications of HCC. Conclusion: The constituent ratio of the severe complication is closely related with the factor of gender and age in HCC death cases.
Keywords:Primary hepatocellular carcinoma  Complication  Death case  Statistic stratification
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