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亚硝酸钠对泥鳅红细胞的遗传损伤研究
引用本文:陈鲤群,陈娜娜,连丽丽,许美轮,吴若菁.亚硝酸钠对泥鳅红细胞的遗传损伤研究[J].海峡预防医学杂志,2008,14(4):11-13.
作者姓名:陈鲤群  陈娜娜  连丽丽  许美轮  吴若菁
作者单位:福建师范大学生命科学学院,福州,350108
基金项目:福建省科技厅重点项目,福州市科技局重点项目 
摘    要:目的]研究亚硝酸钠在不同浓度和不同染毒时间对泥鳅红细胞的损害,观察改性竹炭-K对亚硝酸钠的吸附效果。方法]用微核率评价亚硝酸钠对泥鳅的红细胞遗传损伤。结果]亚硝酸钠的损害主要表现在微核率以及核变形率的增高,且在一定浓度范围内,随着浓度的升高和染毒时间的延长而越来越高。用改性竹炭-K对400mg/L的亚硝酸钠吸附处理,效果显著。结论]亚硝酸钠对泥鳅的LD50为272mg/L;对泥鳅的遗传损伤表现为微核率和核变形率增高;改性竹炭-K对亚硝酸钠的吸附作用显著。

关 键 词:亚硝酸钠  泥鳅  红细胞  遗传损伤  改性竹炭-K

Study on the Genetic Damage to Red Blood Cell of Loach by NaNO2
CHEN Li-Qun,CHEN Na-Na,LIAN Li-Li,et al..Study on the Genetic Damage to Red Blood Cell of Loach by NaNO2[J].Strait Journal of Preventive Medicine,2008,14(4):11-13.
Authors:CHEN Li-Qun  CHEN Na-Na  LIAN Li-Li  
Institution:CHEN Li-Qun; CHEN Na-Na; LIAN Li-Li. et al. (Life Science College of Fujian Normal University, Fuzhou 350108, China )
Abstract:Objective] To study the genetic damage to red blood cell of loach by different concentrations and exposure time of NaNO2,and observe the absorption effect of modified bamboo charcoal-K.Methods] Micro-nuclear rate was used to evaluate the genetic damage to red blood cell of loach by NaNO2.Results] The main genetic damage by NaNO2 showed the increased rates of micro-nuclear and nuclear deformation.And at a certain concentration ranges,the micro-nuclear rate increased significantly with the increasing of concentration and exposure time of NaNO2.Modified bamboo charcoal-K existed obvious adsorption function at 400 mg/L concentration.Conclusion] The LD50of NaNO2to loach is 272 mg/L;The main genetic damage by NaNO2 shows the increased rates of micro-nuclear and nuclear deformation.And modified bamboo charcoal-K shows good adsorption function to NaNO2.
Keywords:NaNO_2  Loach  Red Blood Cell  Genetic Damage  Modified Bamboo Charcoal-K
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