四肢长骨骨巨细胞瘤手术治疗

目的比较不同手术方法治疗四肢长骨骨巨细胞瘤的临床效果。方法回顾分析1998年11月至2006年4月手术治疗的37例四肢长骨骨巨细胞瘤。结果37例患者均获得随访，随访时间8个月至7年2个月，平均2年11个月。病灶刮除＋酒精灭活＋骨水泥填充术21例，肿瘤复发3例；病灶刮除＋酒精灭活＋骨水泥填充植骨术12例，肿瘤复发3例；瘤段切除人工假体置换术4例，肿瘤复发0例。病灶刮除组总复发率18．2％，瘤段切除组织复发率为0。结论病灶刮除＋酒精灭活＋骨水泥填充术和肿瘤瘤段切除术均是治疗骨巨细胞瘤的可靠方法。

Surgery Therapy of Giant Cell Tumor of Long Bones in Extremities

Objective To evaluate the clinical results of the giant cell tumors of long bones treated by surgery.Methods To analyze retrospectively 37 patients with giant cell tumors in extremities treated by curettage and en block resection from November 1998 to April 2006.Results All the 37 cases were followed up for 2 years and 11 months in average(8 months-7 years and 2 months),3 of 21 cases treated with curettage,devitalizing with 95% alcohol and packing with cement recurred;3 of 12 cases treated with curettage,devitalizing with 95% alcohol and packing with cement and bone grafting recurred;None of 4 case treated with block resection and artificial joint prosthetic replacement recurred.The local recurrence rate was 18.2% in the curetted group and 0% in the block resection group.Conclusion Both curettage,devitalizing with 95% alcohol,and packing with cement and en block resection are an effective and safe method in treatment of giant cell tumors of long bones.