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吴茱萸中的黄酮苷类化合物
引用本文:胡传芹,杨鑫宝,杨秀伟,刘建勋. 吴茱萸中的黄酮苷类化合物[J]. 中国中药杂志, 2012, 37(17): 2571-2575
作者姓名:胡传芹  杨鑫宝  杨秀伟  刘建勋
作者单位:1. 北京大学天然药物及仿生药物国家重点实验室药学院天然药物学系,北京,100191
2. 北京中医药大学,北京100029;中国中医科学院西苑医院,北京100091
基金项目:国家"十二五"科技支撑计划项目(2011BAI07B08)
摘    要:目的:研究吴茱萸的化学成分.方法:应用溶剂法和色谱法分离纯化化合物,利用谱学技术鉴定化合物结构.结果:从吴茱萸70%乙醇溶液提取物的正丁醇萃取部分分离得到15个化合物,该文报道其中4个黄酮苷类化合物的结构,分别为香叶木素-7-O-β-D-吡喃葡萄糖苷(1),异鼠李素-3-O-芸香糖苷(2),香叶木苷(3)和柯伊利素-7-0-芸香糖苷(4).结论:化合物1,3,4均为首次从吴茱萸中分离得到.

关 键 词:吴茱萸  芸香科  黄酮苷  化学成分
收稿时间:2012-03-03

Flavonoid glycosides from dried and nearly ripe fruits of Evodia rutaecarpa
HU Chuan-qin,YANG Xin-bao,YANG Xiu-wei and LIU Jian-xun. Flavonoid glycosides from dried and nearly ripe fruits of Evodia rutaecarpa[J]. China Journal of Chinese Materia Medica, 2012, 37(17): 2571-2575
Authors:HU Chuan-qin  YANG Xin-bao  YANG Xiu-wei  LIU Jian-xun
Affiliation:State Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China;Beijing University of Chinese Medicines, Beijing 100029, China;Xiyuan Hospital, China Academy of Chinese Sciences, Beijing 100091, China;State Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China;Beijing University of Chinese Medicines, Beijing 100029, China;Xiyuan Hospital, China Academy of Chinese Sciences, Beijing 100091, China
Abstract:Objective: To study the chemical constituents from the dried and nearly ripe fruits of Evodia(Euodia)rutaecarpa.Method: The compounds were separated and purified by solvent and chromatographic methods.Their structures were identified by spectroscopic techniques.Result: Fifteen compounds were separated from the normal butanol extracts of the 70% aqueous ethanol extract of the dried and nearly ripe fruits of E.rutaecarpa.Among of them,four compounds were reported in the essay and identified as diosmetin-7-O-β-D-glucopyranoside(1),isorhamnetin-3-O-rutinoside(2),diosmin(3) and chrysoeriol-7-O-rutinoside(4).Conclusion: Compounds 1,3 and 4 were separated from the dried and nearly ripe fruits of E.rutaecarpa for the first time.
Keywords:Evodia rutaecarpa  rutaceae  flavonoid  chemical constituent
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