Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans |
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Authors: | Marschall Hanns-Ulrich Wagner Martin Zollner Gernot Fickert Peter Diczfalusy Ulf Gumhold Judith Silbert Dagmar Fuchsbichler Andrea Benthin Lisbet Grundström Rosita Gustafsson Ulf Sahlin Staffan Einarsson Curt Trauner Michael |
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Affiliation: | Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden. hanns-ulrich.marschall@medhs.ki.se |
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Abstract: | |
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Keywords: | 4β-OH-C, 4β-hydroxy cholesterol BAAT, bile acid amino transferase BSEP, bile salt export pump C4, 7α-hydroxy-4-cholesten-3-one CA, cholic acid CYP, cytochrome P450 DCA, deoxycholic acid HCA, hyocholic acid LCA, lithocholic acid CDCA, chenodeoxycholic acid HDCA, hyodeoxycholic acid MDR, multidrug resistance protein MRP, multidrug resistance-related protein OATP, organic anion transporting polypeptide PBC, primary biliary cirrhosis RIFA, rifampicin UGT, uridine diphosphate glucuronosyltransferase UDCA, ursodeoxycholic acid |
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