Perianal ulcerations from topical steroid use

Topical steroids play an extremely important role in the treatment of various dermatologic conditions. Use of topical steroids must be approached with caution, however, as they can have serious side effects. We report a case of iatrogenic perianal ulcers caused by twice-daily application of Lotrisone (clotrimazole and betamethasone dipropionate) in the perianal region. High-potency topical steroids should be used sparingly and briefly in intertriginous areas.