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肺泡蛋白沉积症的临床诊治分析
引用本文:马祥,姚蓉,王茂筠,杨小东,王佑娟,谢敏,孙凯,梁宗安.肺泡蛋白沉积症的临床诊治分析[J].西部医学,2007,19(6):1070-1072.
作者姓名:马祥  姚蓉  王茂筠  杨小东  王佑娟  谢敏  孙凯  梁宗安
作者单位:四川大学华西医院呼吸内科,四川,成都,610041
摘    要:目的提高对肺泡蛋白沉积症(PAP)的认识,从而实现对PAP的早期诊断与治疗。方法回顾性分析经病理检查确诊的8例PAP患者的临床资料。结果8例PAP患者中6例行支气管肺泡灌洗,灌洗术后患者的临床症状、血气、胸部CT均有明显改善。结论PAP的主要临床症状为进行性呼吸困难、气促、咳嗽。胸部CT的典型表现为两肺野呈"地图样"分布的磨玻璃影、斑片影以及分布于其中的网格状影。根据病理进行确诊。支气管肺泡灌洗是目前唯一有效的治疗方法。

关 键 词:肺泡蛋白沉积症  早期诊断  支气管肺泡灌洗
文章编号:1672-3511(2007)06-1070-03
修稿时间:2007-07-31

Clinical diagnosis of pulmonary alveolar proteinosis
MA Xiang,YAO Rong, WANG Mao-yun, et al.Clinical diagnosis of pulmonary alveolar proteinosis[J].Medical Journal of West China,2007,19(6):1070-1072.
Authors:MA Xiang  YAO Rong  WANG Mao-yun  
Institution:Department of Respiratory Diseases, West China Hospital, Sichuan University, Chengdu 610041,China
Abstract:Objective To improve the diagnosis and treatment of pulmonary alveolar proteinosis(PAP) in clinic.Methods A retrospective analysis of 8 cases diagnosed as pulmonary alveolar proteinosis(PAP)by pathological examinations from May 2003 to May 2007 was made.Results Six patients receiving bronchoalveolar lavage had significant improvement in clinical manifestation,artery blood gas analysis and chest CT scan.Conclusion The chief clinical manifestation is progressive dyspnea,breathlessness and cough.Chest CT scanning shows that ground glass shadow,patch shadow and reticular shadow are map-liked located in both lung fields.The diagnosis should be made with pathological evidences.So far,bronchoalveolar lavage is the only effective treatment for PAP.
Keywords:Pulmonary alveolar proteinosis  Early diagnosis  Bronchoalveolar lavage
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