Medication-taking behavior in hypertensive patients with a single-tablet,fixed-dose combination in Japan |
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| Authors: | Ikuo Saito Toshio Kushiro Yasuyuki Matsushita Yuki Sato Kei Sagawa Yuko Tanaka |
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| Affiliation: | 1. Keio University Health Center, Kanagawa, Japan, saitoikuokeiouniv@gmail.com;3. The Life Planning Center Foundation, Tokyo, Japan,;4. Daiichi Sankyo Co., Ltd, Tokyo, Japan, and |
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| Abstract: | Non-persistence rate (defined as not remaining on treatment) in patients taking a renin angiotensin system inhibitor plus calcium channel blocker was studied in three integrated 12-weeks surveys by matching separate drug combination therapy (CT) and fixed-dose combination (FDC). We also investigated medication adherence measured by proportion of days covered by using a claims database. The non-persistence rate was significantly lower in FDC than CT (p?=?0.0074). In the database study, the medication adherence was higher in FDC than CT for 3, 6, and 12 months (all p?
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| Keywords: | Azelnidipine fixed-dose combination medication-taking behavior olmesartan Rezaltas |
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