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The new steroidal glycosides from the aerial parts of Lepidogrammitis drymoglossoides
Authors:Hua Wei  Hai Jiang  Zhu-Xiang Liu  Gui Li  Hua Long  Jian-Wu He
Affiliation:1. Key Laboratory of Plant Resource Conservation and Utilization (Jishou University), College of Hunan Province, Jishou 416000, China;2. Institute of Medicinal Plant Development, Beijing 100193, China;3. Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, Harbin 150040, China
Abstract:Two new steroidal glycosides ponasteroside C (1) and ponasteroside D (2) were isolated from the aerial parts of Lepidogrammitis drymoglossoides. Their structures were elucidated by various spectroscopic techniques (IR, HRESIMS, 1D and 2D NMR). All compounds were evaluated for their cytotoxicity against HeLa and HCT-8 cell lines, and compounds 1 and 2 showed mild activity against all the test cell lines.
Keywords:Polypodiaceae  Lepidogrammitis drymoglossoides  steroidal glycosides  cytotoic activity
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