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The status of diabetic embryopathy
Authors:Ulf J. Eriksson  Parri Wentzel
Affiliation:1. Department of Medical Cell Biology, Uppsala University, Biomedical Center, Uppsala, Swedenulf.eriksson@mcb.uu.se;3. Department of Medical Cell Biology, Uppsala University, Biomedical Center, Uppsala, Sweden
Abstract:Diabetic embryopathy is a theoretical enigma and a clinical challenge. Both type 1 and type 2 diabetic pregnancy carry a significant risk for fetal maldevelopment, and the precise reasons for the diabetes-induced teratogenicity are not clearly identified. The experimental work in this field has revealed a partial, however complex, answer to the teratological question, and we will review some of the latest suggestions.
Keywords:Anomalies  development  diabetes in pregnancy  epigenetics  gene expression  malformations
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