| 生精散胶囊对小鼠生殖能力改善作用机制的探讨 |
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| 引用本文： | 孙伟,管群,杨伟娜. 生精散胶囊对小鼠生殖能力改善作用机制的探讨[J]. 辽宁中医药大学学报, 2009, 0(4) |
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| 作者姓名： | 孙伟 管群 杨伟娜 |
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| 作者单位： | 山东中医药大学第二附属医院生殖中心;山东中医药大学; |
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| 摘 要： | 目的:探讨生精散胶囊对小鼠生殖能力改善的作用机制。方法:对比肾阳虚小鼠使用生精散胶囊治疗前后其生殖激素水平及SOD、MDA的变化。结果:肾阳虚小鼠灌胃生精散胶囊治疗后血FSH、LH、T、GnRH均明显升高(P<0.05),小鼠附睾组织匀浆MDA浓度明显降低,而SOD浓度显著升高(P<0.05)。结论:生精散通过调节垂体-下丘脑-性腺轴的功能来调节生精过程,并且可增强体内抗氧化酶活性,增强附睾功能,从而发挥抗氧化作用,保护附睾精子免受氧化损伤。
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| 关 键 词： | 肾阳虚 生精散 生殖激素 抗氧化作用 |
Explore the Mechanism of Sheng Jing San Capsule to Improve the Reproductive Ability of Mice |
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| SUN Wei,GUAN Qun,YANG Wei-na. Explore the Mechanism of Sheng Jing San Capsule to Improve the Reproductive Ability of Mice[J]. Journal of Liaoning University of Traditional Chinese Medicine, 2009, 0(4) |
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| Authors: | SUN Wei GUAN Qun YANG Wei-na |
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| Affiliation: | 1.The Second Affiliated Hospital of Shandong University of Chinese Medicine;Ji'nan 250001;Shandong;China;2.Shandong University of Chinese Medicine;Ji'nan 250355;China |
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| Abstract: | Objective: To explore the mechanism of Sheng Jing San capsule to improve the reproductive ability of mice.Method: To compare the reproductive hormone levels and SOD,MDA in mice with deficiency of Kidney Yang before and after use the Sheng Jing San capsule.Results: The Sheng Jing San capsule group comparing to the model group as follow: the containment of GnRH,LH,FSH,and T in the blood become higher(P<0.05),containment of MDA in the epididymis tissue was lower,and concentration of SOD increased(P<0.05).Concl... |
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| Keywords: | deficiency of kidney yang Sheng Jing San capsule reproductive hormone antioxidant |
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