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| 梅尼埃病的相关免疫因素研究 | |
| 引用本文： | 谭长强,曹银成,刘桦,祝纪山,何学勤,杜彩琳,周鸣. 梅尼埃病的相关免疫因素研究[J]. 临床耳鼻咽喉头颈外科杂志, 1998, 12(5): 208-210 |
| 作者姓名： | 谭长强 曹银成 刘桦 祝纪山 何学勤 杜彩琳 周鸣 |
| 作者单位： | 1. 南京铁道医学院附属医院耳鼻咽喉科,210009 2. 南京铁道医学院药理教研室 3. 南京铁道医学院寄生虫教研室 4. 南京医科大学第二附属医院耳鼻咽喉科 |
| 摘 要： | 为研究梅尼埃病患者相关性特异性免疫不指标和针对内耳组织抗原特异性体液与细胞免疫反应的变化，采用免疫学实验技术，对梅尼埃患者于发作期和间歇期进行免疫学检测，并与无耳病者进行对照。结果示，部分患者发作期血清免疫球蛋白和补体含量，以及非特异性淋巴细胞转化率升高，循环免疫复合物和抗核抗体与抗核内可溶性抗原抗体阳性，并出现特异性抗体和细胞免疫的反应。 |
| 关 键 词： | 梅尼埃病 免疫反应 内耳眩晕 |
The clinical study of immune factors relative to Meniere''''s disease |
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| Tan Changqiang, Cao Yincheng, Liu Hua et al. The clinical study of immune factors relative to Meniere''''s disease[J]. Journal of clinical otorhinolaryngology, head, and neck surgery, 1998, 12(5): 208-210 | |
| Authors: | Tan Changqiang Cao Yincheng Liu Hua et al |
| Affiliation: | Department of Otolaryngology, Affiliated Hospital of Nanjing, Railway Medical College, Nanjing 210009. |
| Abstract: | It was investigated that the clinical unspecialized immunological factors and special immune reaction against to inner ear antigens relate with the cause of Meniere's disease. Every of the relative immune tests and special humoral and cellular immune reaction tests were proceeded in the breaking out and intermittent period of Meniere's disease patients, and the normal controls. The levels of IgG and C3 in serum and unspecialized lympyocyte blastogenesis increased, and positive of circular immune compound and antibody against cellular nucleus,and special humoral and cellular immune reaction against inner ear antigens during the breaking out period of the patients. Theelement of inner ear autoimmune could play an important role in the pathogenical mechanism of some patients with Meniere's disease. |
| Keywords: | Meniere's disease Autoimmune disease Immune reaction |
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