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甘露醇外渗后局部组织损伤处理的实验研究
引用本文:韩雪玲,胡淑芳,张文香,杨喜民,赵永霞,王明兰.甘露醇外渗后局部组织损伤处理的实验研究[J].中华护理杂志,2002,37(4):260-261.
作者姓名:韩雪玲  胡淑芳  张文香  杨喜民  赵永霞  王明兰
作者单位:721004,宝鸡市,中国人民解放军第三医院神经外科研究所
摘    要:目的 :根据甘露醇外渗后局部组织损伤的特点寻找理想的处理方法。方法 :制作两种甘露醇外渗动物模型 (模型Ⅰ为单纯性甘露醇外渗 ,模型Ⅱ为甘露醇外渗伴局部瘀血 ) ,分别采用临床常用的 3种处理方法进行动物实验 ,进行肉眼观察及组织学观察。结果 :5 0 %硫酸镁湿敷对模型Ⅰ的疗效明显优于其他方法 ;0 .2 5 %奴夫卡因封闭对模型Ⅱ的疗效最佳。同时显示模型Ⅱ较模型Ⅰ的组织损伤程度重 ,修复难度大。结论 :临床处理甘露醇外渗应根据其局部特点选择合理有效的处理方法。

关 键 词:甘露醇  诊断和治疗物质外渗  疾病模型  动物
修稿时间:2001年8月13日

Experimental study of regional injury and its treatment following extravasation of mannitol
HAN Xueling,HU Shufang,ZHANG Wenxiang,et alResearch Institute of Neurosurgry,the No. Hospital of PLA,Baoji,shanxi province.Experimental study of regional injury and its treatment following extravasation of mannitol[J].Chinese Journal of Nursing,2002,37(4):260-261.
Authors:HAN Xueling  HU Shufang  ZHANG Wenxiang  Research Institute of Neurosurgry  the No Hospital of PLA  Baoji  shanxi province
Institution:HAN Xueling,HU Shufang,ZHANG Wenxiang,et alResearch Institute of Neurosurgry,the No.3 Hospital of PLA,Baoji,shanxi province,721004
Abstract:Objective:To investigate the effects of extravasation of mannitol and to found the best methods to cure it.Methods:There are two models in our experiment (Model I:Simple extravasation of mannitol.Model II:Regional extravastated blood following extravasation of mannitol) and three methods were used.Results:In model I,the effect of magnesium sulphate is more obvious than the others.In mold II,the effect of novocaine is the best.There is severe injury in model II,and the repair in model I is more difficult.Conclusion:different cure model should be used by its regional character in clinic.
Keywords:Mannital  Extravasation of diagnostic and therapeutic matirials  Disease models  animal
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