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#65 Medication use,co-morbidity and injury in older male farmers
Affiliation:1. Immunisation, Hepatitis and Blood Safety Department, Public Health England, London, UK;2. North London Health Protection Team, Public Health England, UK;3. NHS England London Region Public Health Department, UK;4. World Health Organization (WHO) Regional Office for Europe, Marmorvej 51, DK-2100 Copenhagen, OE, Denmark;5. NIHR Health Protection Research Unit in Immunisation, London School of Hygiene and Tropical Medicine, London, UK;6. Field Epidemiology Service, National Infections Service, Public Health England, London, UK;1. Doctoral School of Science and Technology (DSST) - Lebanese University, Rafic Hariri University Campus, Hadath, Lebanon;2. Laboratoire de Biotechnologie des Substances Naturelles et Produits de Santé (BSNPS), Doctoral School of Sciences and Technology, Lebanese University, Rafic Hariri University Campus, Hadath, Lebanon;3. Faculty of Pharmacy - Lebanese University, Rafic Hariri University Campus, Hadath, Lebanon;4. Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon;1. School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong;2. Harvard Medical School, Harvard University, Boston, MA, USA;3. Department of Medicine & Geriatrics, The Princess Margaret Hospital, Hospital Authority, Hong Kong;4. Department of Microbiology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong;1. Sigmovir Biosystems, Inc, 9610 Medical Center Drive, Suite 100, Rockville, MD 20850, USA;2. Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), 10903 New Hampshire Avenue, Silver Spring, MD 20993, USA;3. University of Rochester Medical Center, Rochester General Hospital, 1425 Portland Avenue, Infectious Diseases Unit, Rochester, NY 14621, USA;1. Department of Paediatric Infectious Diseases and Immunology, Wilhelmina Children’s Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands;2. Department of Methods and Statistics, Tilburg University, Tilburg, The Netherlands;3. Department of Paediatric Intensive Care, Alder Hey Children’s Hospital, Liverpool, United Kingdom;4. Department of Paediatric Intensive Care, Wilhelmina Children’s Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands;5. Department of Paediatric Intensive Care, Emma Children’s Hospital, Academic Medical Centre, Amsterdam, The Netherlands;6. Department of Paediatric Pulmonology, Wilhelmina Children’s Hospital, University Medical Centre Utrecht, The Netherlands;7. Laboratory of Translational Immunology, Department of Immunology, University Medical Centre Utrecht, Utrecht, the Netherlands;1. Agricultural Research Council – Onderstepoort Veterinary Research, Private Bag X5, Onderstepoort 0110, South Africa;2. Department of Microbiology and Plant Pathology, Faculty of Natural and Agricultural Sciences, University of Pretoria, South Africa;3. National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, MB, Canada;4. Department of Immunology, University of Manitoba, Winnipeg, MB, Canada;5. Department Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, South Africa
Abstract:PURPOSE: The purpose of this research was to determine if there is a potentially causal relationship between medication use and injury among older male farmers in Alberta.METHODS: Using probabilistic linkage between an Alberta Agriculture government registry of farm operators and the Alberta Health Plan registry file, older farmers (aged 66 and older) were identified. Farm related injuries were identified using an E-code search of both hospitalization and emergency department separations for a 3-year period. Cases were matched to controls on age, geographic health region, and index injury date at a ratio of 5:1. Co-morbidity and medication use for each of the cases and controls were derived from population based health system utilization files. Conditional logistic regression was used to determine which medications were related to injury.RESULTS: Over a 3-year period, a total of 282 farm related injuries were suffered by the linked group. Controlling for co-morbidity, farmers who had stopped taking narcotic pain killers (OR = 9.85[95%CI:5.14,18.86]) and non-steroidal anti-inflammatories (OR = 2.36[95%CI:1.40,3.98]) 30 days prior to the date of injury were at increased risk. Those farmers taking sedatives and hypnotics right up until the date of injury were also at increased risk (OR = 3.12[95CI:1.41,6.89]).. In addition, those suffering from incontinence (OR = 3.71[95%CI:1.60,8.59]) and osteoporosis (OR = 4.78[95%CI:1.34,16.99]) were also at increased risk.CONCLUSION: The relationship of medication use and injury in this population is different from those observed in studies of falls in older persons. These data indicate that distraction from either pain or co-morbidity may play a factor in injuries suffered in this active older working population.
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