| 血浆置换成功治疗血栓性血小板减少性紫癜12例报道 |
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| 引用本文： | 彭侃夫,赵洪雯,余荣杰,孙岩,王军霞,吴亿,吴雄飞. 血浆置换成功治疗血栓性血小板减少性紫癜12例报道[J]. 重庆医学, 2008, 37(8): 815-817 |
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| 作者姓名： | 彭侃夫 赵洪雯 余荣杰 孙岩 王军霞 吴亿 吴雄飞 |
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| 作者单位： | 第三军医大学西南医院肾科,重庆,400038;第三军医大学西南医院肾科,重庆,400038;第三军医大学西南医院肾科,重庆,400038;第三军医大学西南医院肾科,重庆,400038;第三军医大学西南医院肾科,重庆,400038;第三军医大学西南医院肾科,重庆,400038;第三军医大学西南医院肾科,重庆,400038 |
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| 摘 要： | 目的观察血浆置换治疗血栓性血小板减少性紫癜(TTP)的疗效。方法12例TTP患者,以新鲜冰冻血浆为置换液,进行血浆置换,每日1次,血浆置换次数中位数为7次(1~9次)。结果血浆置换治疗12例患者中10例存活。血浆置换治疗后12~72h,10例存活患者清醒;血浆置换4次后发热消退,皮下无新鲜出血点和淤斑,黄疸消失,红细胞压积和血小板数逐渐升高。结论血浆置换治疗TTP疗效好,值得推广。
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| 关 键 词： | 血栓性血小板减少性紫癜 血浆置换 |
| 文章编号： | 1671-8348(2008)08-0815-02 |
| 修稿时间： | 2007-12-05 |
Efficacy of plasma exchange in treatment of patients with thrombotic thrombocytopenic purpura |
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| PENG Kan-fu,ZHAO Hong-wen,YU Rong-jie,et al.. Efficacy of plasma exchange in treatment of patients with thrombotic thrombocytopenic purpura[J]. Chongqing Medical Journal, 2008, 37(8): 815-817 |
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| Authors: | PENG Kan-fu ZHAO Hong-wen YU Rong-jie et al. |
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| Abstract: | Objective To observe the effect of plasma exchange(PE)on patients with thrombotic throbocytopenic purpura (TTP).Methods 12 patients received PE and drugs treatment (including glucocorticoid and anti-platelet drugs).PE was performed with fresh-frozen plasma every day,and median of PE treatment was 7 times(1 to 9 times).Results 10 patients with PE treatment were survival.Within 12-72h after the plasma treatment,neurological and psychiatric symptoms ameliorated. After 4 times of PE treatment, hematocrit and platelet increased gradually, and fever, novel petechia,purpura and jaundice were not observed again in the survival patients.Conclusion PE is good choise for TTP. |
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| Keywords: | thrombotic throbocytopenic purpura plasma exchange |
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