缓释异搏停治疗高血压疗效初步报告 |
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引用本文: | 邵耕,李琳,张树彬,王增顺,周荣彦.缓释异搏停治疗高血压疗效初步报告[J].北京大学学报(医学版),1989(6). |
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作者姓名: | 邵耕 李琳 张树彬 王增顺 周荣彦 |
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作者单位: | 北京医科大学第一医院心内科
(邵耕,李琳,张树彬,王增顺),北京医科大学第一医院心内科(周荣彦) |
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摘 要: | 以单盲安慰剂对照观察缓释异搏停(VR_(SR))对33例高血压(轻、中度)患者的疗效,初步结果说明VR_(SR)组(25例)血压有明显下降(P<0.01),和安慰剂组(8例)血压改变比较有显著性差别(P<0.01,P<0.05:总有效率为72%,72%的患者VR_(SR)的剂量为240~360 mg/日。未观察到明显副作用。
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关 键 词: | 缓释异搏停 高血压 |
PRELIMINARY REPORT ON EFFECTS OF THE TREATMENT OF HYPERTENSION WITH VERAPAMIL SLOW RELEASE FORMULATION |
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Institution: | Department of Cardiology,The First Hospital Shao Geng |
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Abstract: | The preliminary results of the treatment of 33 mild or moderate hypertensive patients with verap-amil slow release formulation (VRsr 240mg film tablet, Knoll AG) by a single blind placebo control trial are reported. There were significant decrease of both systolic and diastolic BP. (P<0.01) and the efficacy rate was 72%. The differences of changes of B P. before and after treatment between the treatment and control groups were significant too (P<0.01, P<0.05). The daily dose of VRsr in 72% of patients was 240mg-360mg/day (60-480mg/day). No obvious side effects were observed. |
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Keywords: | Hypertension Verapamil slow release formulation |
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