| 直肌离断对虹膜睫状体的脂质过氧化损伤 |
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| 引用本文： | 李珍,章应华.直肌离断对虹膜睫状体的脂质过氧化损伤[J].眼科研究,1994,12(2):89-91. |
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| 作者姓名： | 李珍 章应华 |
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| 作者单位： | 西安第四军医大学唐都医院眼科，青岛海军４０１医院眼科 |
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| 摘 要： | 实验测定了犬眼不同组合的２条和３条直肌离断后虹膜眼下状体组织脂质过氧化反应产物丙二醛含量和超氧化物岐化酶活性，并观察了睫状体非色素上皮细胞的超微结构，发现２条直肌离断术后１、３、７天，ＭＤＡ和ＳＯＤ变化不显著。３条直肌离断术后１、３天ＭＤＡ含量明显升高，ＳＯＤ活性显著降低，术后７天变化不显著，超微结构示细胞内膜性结构受损，提示３条直肌同时离断眼前节缺血早期，超氧自由基大量产生引发的脂质过氧化损伤，
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| 关 键 词： | 直肌离断 眼前节缺血 过氧化脂质 |
Lipid Peroxidation of Iris and Ciliary Body Following Recti Tenotomy |
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| Li Zhen,Zhang
Yinghua.Lipid Peroxidation of Iris and Ciliary Body Following Recti Tenotomy[J].Chinese Ophthalmic Research,1994,12(2):89-91. |
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| Authors: | Li Zhen Zhang
Yinghua |
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| Institution: | Li Zhen,Zhang
Yinghua Department of Ophthalmology,Second Teaching Hospital,the Fourth Military Medical
Uni-versity,Xian |
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| Abstract: | enotomy of two and three recti in different combinations was done in
32 adult dog eyes. The content ofMalondialdehyde (MDA)and the activity of superoxide
dismutase(SOD)in iris and ciliary body were deter-mined. The ultrastructure of ciliary epithelial
cells was observed. The results showed that in eyes with tenoto-my of three recti MDA was
significantly higher and SOD was significantly lower than that of the control(P< 0. 05)one and
three days after operation. But these changes were not significant in seven
days(P>0.05).Cel-lular membrane structures of ciliary epithelium was damaged.There were no
remarkable changes in eyes withtenotomy of two recti.It is suggested that lipid peroxidation
initiated by superoxygenic free radical plays animportant role in the occurrence of anterior
segment ischemia(ASI). |
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| Keywords: | recti tenotomy anterior segment ischemia malondialdehyde superoxide dismutase lipidperoxidation |
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