| 铅对视网膜脂肪酸组成及含量影响的实验研究 |
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| 引用本文： | 李蕴季 于纯智. 铅对视网膜脂肪酸组成及含量影响的实验研究[J]. 眼科研究, 1994, 12(3): 161-163 |
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| 作者姓名： | 李蕴季 于纯智 |
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| 作者单位： | 西安第四军医大学西京医院眼科，乌鲁木齐市军区总医院眼科，第四军医大学化学教研室 |
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| 摘 要： | 用气相色谱法测定了正常兔眼，置入铅块及置入玻璃块兔视网膜脂肪酸的组成及含量。置入铅块眼２周后不饱和脂肪酸Ｃ１８：１开始升高，８周时不饱和脂肪酸Ｃ１８：１，Ｃ１８：２，Ｃ２０：４显著升高，而饱和脂肪酸Ｃ１６：０，Ｃ１８：１明显降低。置入玻璃块眼与正常眼基本一致。上述结果提示铅干扰了视网膜脂肪酸代谢。
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| 关 键 词： | 铅 脂肪酸 视网膜 兔 眼内异物 |
Effect of Lead on the Composition and Content of Retinal Fatty Acids: An Experimental Study |
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| Li Yunxiu,et al. Effect of Lead on the Composition and Content of Retinal Fatty Acids: An Experimental Study[J]. Chinese Ophthalmic Research, 1994, 12(3): 161-163 |
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| Authors: | Li Yunxiu et al |
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| Affiliation: | Li Yunxiu,et al Department of Ophtalmology,Xijing Hospital,Fourth Military Medical University,Xian |
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| Abstract: | he composition and content of retinal fatty acids in normal rabbit eyes, eyes containing a lead splinter and eyes containing a glass splinter were measured by gas chromatography.The results showed that two weeks after the implantation of the lead splinter the content of the unsaturated fatty acid C18:1 began to in- crease. By the eighth week the contents of all the unsaturated fatty acids(C18:1, C18:2,C20:4)were significantly higher than those in normal eyes, whereas the contents of the saturated fatty acids(C16:0,C18:0)decreased.No difference existed between the normal eyes and the eyes containing a glass splinter. The results indicate that lead interferes with the metabolism of retinal fatty acids. |
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| Keywords: | lead fatty acid retina rabbit |
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