| 消炎痛防治电光性眼炎的研究 |
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| 引用本文： | 翁景中,胡椿枝.消炎痛防治电光性眼炎的研究[J].眼科研究,1994,12(1):7-9. |
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| 作者姓名： | 翁景中 胡椿枝 |
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| 作者单位： | 武汉同济医科大学附属协和医院眼科，福建医学院附属协和医院眼科 |
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| 摘 要： | 采用放免方法测定正常家兔角膜上皮内ＰＧＥ１、ＰＧＥ２、ＰＧＦ２α、ＰＧＩ２、ＴＸＡ２等前列腺素含量。并在紫外线照射前后分别采用０．２５％消炎痛油型滴剂滴眼。６小时后再次测定兔角膜上皮内ＰＧ５，发现ＰＧＥ、ＰＧＥ２、ＰＧＩ２和ＴＸＡ２合成均受到明显抑制（Ｐ＜０．０５－０．０１），且角膜炎症症反应较轻。但照射前后用药对角膜上皮内ＰＧ５合成的抑制无显著性差异（Ｐ＞０．０５）。结果提示前列腺素在电光性眼炎
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| 关 键 词： | 消炎痛 紫外线 电光性眼炎 |
Topical Use of Indomethacin in the Prevention of Electrokeratitis |
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| Weng Jingning,et
al.Topical Use of Indomethacin in the Prevention of Electrokeratitis[J].Chinese Ophthalmic Research,1994,12(1):7-9. |
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| Authors: | Weng Jingning et
al |
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| Institution: | Weng Jingning,et
alDepartment of Ophthalmology,Union Hospital Affiliated to Tongji Medical University,Wuhan |
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| Abstract: | e detected the prostaglandings in normal corneal epithelium using RIA. Topical
dropping 0.25%in-domethacin oil drop in preirradiating and postirradiating ,respectively. We
discovered PGS(PGE1 ,PGE2 ,PGI,TXA)synthesis to be inhibited dramatically(p< 0.05-0.01) ,and
the reaction to UV was rather less in 6hours after UV irradiation. But the effect of preirradiating
administration was not different with that of po-stirradiating (P>0.05).The results of experiments
suggested that the PGs play an important role in electro-keratitis and 0.25%indomethacin oil
drop can be used for preventing the disease. |
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| Keywords: | prostaglanding indomethacin electrokeratitis |
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