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甲硝唑乳膏的制备及质量控制
引用本文:兰顺,荆树汉,叶冬梅,符翠莉. 甲硝唑乳膏的制备及质量控制[J]. 药学实践杂志, 2004, 22(5): 289-290
作者姓名:兰顺  荆树汉  叶冬梅  符翠莉
作者单位:广西壮族自治区人民医院,广西,南宁,530021
摘    要:目的:制备甲硝唑乳膏并建立其质量控制标准。方法:以甲硝唑为主药制备甲硝唑乳膏,采用紫外分光光度法测定甲硝唑乳膏中甲硝唑的含量。结果:甲硝唑的平均回收率为100.2%,RSD为1.7%。结论:该制剂处方及工艺具有生产可行性,其质量控制标准符合《中国药典》要求,含量测定方法简单、快速、准确。

关 键 词:甲硝唑  乳膏  质量控制
文章编号:1006-0111(2004)05-0289-02
收稿时间:2004-02-06
修稿时间:2004-02-06

Preparation and quality control of metronidazole cream
LAN Shun,JING Shu-han,YE Dong-mei and FU Cui-Ii. Preparation and quality control of metronidazole cream[J]. The Journal of Pharmaceutical Practice, 2004, 22(5): 289-290
Authors:LAN Shun  JING Shu-han  YE Dong-mei  FU Cui-Ii
Affiliation:People's Hospital of Guangxi Zhuangzu Autonomous Region, Nanning 530021, China;People's Hospital of Guangxi Zhuangzu Autonomous Region, Nanning 530021, China;People's Hospital of Guangxi Zhuangzu Autonomous Region, Nanning 530021, China;People's Hospital of Guangxi Zhuangzu Autonomous Region, Nanning 530021, China
Abstract:Objective: To prepare metronidazole cream and establish quality control standard. Methods: The cream was prepared by taking metronidazole as main components. The contents of metronidazole was determined by UV spectrometry. Results:The average recovery of metronidazole was 100. 2% , RSD was 1. 7% . Conclusion:The cream can be prepare feasibly. The method of quality control is simple,rapid and accurate.
Keywords:metronidazole  cream  quality control
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