环状RNA的研究进展

环状RNA(circular RNA,circRNA)又称环形RNA,是新近确认的一类特殊的非编码RNA(ncRNA),主要由外显子和(或)内含子构成。近年来研究发现,在某些疾病(如肿瘤、动脉粥样硬化、糖尿病、神经系统疾病)的发生发展过程中circRNA起着重要的调控作用,这不仅使我们对环状RNA有了更好认识,而且在某些疾病的诊断、治疗及预防方面也为我们提供了新的研究方向。

Research progress of circular RNA

【Abstract】 Circular RNA （circ RNA），is a special kind of newly confirmed noncoding RNA（ncRNA），is mainly composed of exons and（or）introns. In recent years，the study found that in some diseases（such as cancer，atherosclerosis，diabetes，neurological diseases）in the process of the development of circRNA plays an important role in regulation, this not only makes us have a better understanding of circular RNA，and in diagnosis，treatment and prevention of certain diseases also provides a new research direction for us.